Vladimir Grubisic

Vladimir Grubisic

Title: Assistant Professor

Department: Biomedical Sciences

School: College of Osteopathic Medicine

Campus: Long Island

Area(s) of Expertise: Neuroscience, Biochemistry, Molecular and cellular biology, Integrative physiology, Neurogastroenterology

Education Credentials: M.D., Ph.D.

Joined New York Tech: 2022


Vladimir “Vlado” Grubisic received his Doctor of Medicine (M.D.) from Zagreb University in Croatia and his Ph.D. degree in Neurobiology from the University of Alabama at Birmingham, where he was a student of renowned neurobiologist Vladimir Parpura. He obtained his postdoctoral training at Michigan State University under the mentorship of Brian D. Gulbransen, Ph.D.

Grubisic’s research area is at the interface of gastroenterology and neuroscience, with an ongoing fascination with understanding the biology and (patho)physiology of glial cells. He developed a particular passion for enteric glia, a unique kind of glial cells residing in the intestinal wall, and their roles in gut health and disease. Grubisic discovered novel mechanisms of glial regulation of basic gut reflexes, such as motility and epithelial secretion. Recently, he investigated the role of enteric glia in the development and resolution of inflammation, how enteric glia regulates neuro-immune interactions in the gut, and glial contribution to chronic abdominal pain and persistent intestinal epithelial barrier dysfunction. The surface of the digestive tube is one of the largest areas in the human body, interacting with the environment, and the increased permeability of the gut wall, or “leaky gut,” has been implicated in many intestinal and extra-intestinal disorders.

The main research focus of the Grubisic laboratory is to understand the role of enteric glia in the gut epithelial barrier function and the epithelial signal transduction. Such efforts are expected to reveal mechanistic underpinnings of the gut-brain axis and open new ways for the discovery of novel and specific therapeutics to treat gastrointestinal and systemic disorders, including inflammatory bowel disease and metabolic, neurodegenerative, and neurodevelopmental diseases.

Recent Projects and Research

Selected Publications

* Authors share co-first authorship

View a Complete List of Published Work

Professional Honors and Awards

Courses Taught at New York Tech

Contact Info

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