Steven Zanganeh

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Steven Zanganeh is an assistant professor of bioengineering at New York Institute of Technology. His research focuses on cancer immunoengineering, with an emphasis on macrophages in the tumor immune landscape, inflammatory responses, iron metabolism, and ferroptosis-based therapies. He aims to develop innovative strategies that harness the immune system's natural mechanisms to improve cancer treatment outcomes.

He earned his Ph.D. in biomedical engineering from the University of Connecticut, where he studied the theranostic applications of nanoplatforms for cancer imaging and therapy. He then completed postdoctoral training at Stanford University's School of Medicine, investigating the immunotherapeutic effects of iron on tumor-associated macrophages and their role in reshaping the tumor immune landscape. His studies demonstrated that iron can reprogram macrophages from an immunosuppressive phenotype to a pro-inflammatory state, ultimately enhancing anti-tumor immunity and inhibiting cancer growth.

Following his time at Stanford, Zanganeh joined Sloan Kettering Cancer Center, where he expanded his work on the tumor immune landscape, focusing on how iron metabolism modulates immune cell interactions in brain tumors and influences tumor progression. His research provided key insights into how nanoparticle-based therapies can alter the tumor immune environment, making cancers more responsive to immunotherapy and conventional treatments.

At New York Tech, Zanganeh continues to explore the complex interplay between cancer, macrophages, and iron metabolism, with the goal of developing novel therapeutic platforms that enhance macrophage-driven tumor suppression. His work has resulted in numerous high-impact publications, books, book chapters, and patents.

Courses Taught at New York Tech

• Engineering Principles in Cell Biology

Contact Info

• stevenz@nyit.edu
• LinkedIn